Therapeutic effects of adipose-derived mesenchymal stem cells combined with glymphatic system activation in prion disease

Therapeutic effects of adipose-derived mesenchymal stem cells combined with glymphatic system activation in prion disease

Blog Article

Abstract There is currently no effective therapy for prion diseases.The glymphatic system is an organized system of perivascular spaces that facilitates the removal of metabolic waste primaluna evo 400 preamp from the brain.This study demonstrates the therapeutic potential of a combination duke waves and fades therapy of adipose-derived mesenchymal stem cells (AdMSCs) and a glymphatic system-activated drug, clonidine, against prion disease.The therapy has the potential to clear PrPSc accumulation, ameliorate astrocytosis, and prolong the survival time of ME7-infected mice.